Innovative Drug Delivery Systems based on Lipids expands Cerbios competencies in topical treatments

AKVANO^®  technology, based on a water-free liquid, opens up a new dimension in topical administration.

AKVANO formulations consist of lipid components which are dissolved in a volatile, water-free solvent mixture. When this formulation is applied onto the skin, the solvent evaporates and a non-occlusive lipid layer is formed in an immediate interaction with the skin surface. This direct deposition of lipids makes the AKVANO  principle fundamentally different from other dosage forms.

With simple formulation and manufacturing abilities, as well as excellent cosmetic properties, the technology will create new possibilities for effective and convenient treatments in the dermatological field.

For the treatment of:

1. wounds and burned skin
2. eczema
3. psoriasis and infection

and delivery of glucocorticoids.

Some of the advantages of AKVANO are:

• Multiple routes of administration: dermal, mucosal, intranasal, buccal, sublingual, ocular, intravaginal, rectal.
• Excellent incorporation of “difficult” drugs
• Ease of administration
• Easy to prepare and store
• Accurate dosing
• Improved compliance

AKVANO is a novel proprietary drug delivery technology. It represents a completely new dosage form consisting of water-free, sprayable liquid formulations in which selected lipids and the active ingredient are dissolved in a volatile solvent.

After applying to the skin, the solvent quickly evaporates leaving a thin, dry, non-occlusive lipid layer containing the active substance on the skin. Immediately the lipid structure is formed it begins to interact with the skin surface enabling the active substance to start working without delay.

Different lipids and solvents can be selected and combined from a large number of commercially available materials to achieve the desired physicochemical properties and optimize the incorporation and function of active components. AKVANO technology is extremely versatile. Around 80 substances have been successfully incorporated in AKVANO to date.